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Mechanisms of Gain Modulation

Understanding how neural circuits adjust their sensitivity to inputs

This review synthesizes our current understanding of how neural circuits adjust their sensitivity to inputs - a process called gain modulation. We discuss how different types of neurons contribute to this fundamental computation and its importance for flexible behavior.

Nature Reviews Neuroscience (2020)

Key Topics:

  • How neural circuits adjust sensitivity to inputs
  • Different neuron types’ contributions to gain modulation
  • Importance for flexible, adaptive behavior

Read the review